Top Prism Alternatives & Competitors

Finding the right software for your business can be challenging, and while Prism is a popular choice, it may not be the perfect fit for everyone. If you're exploring Prism alternatives, you're in the right place. We’ve compiled a list of the top competitors that offer similar features, pricing, and benefits. Compare the best alternatives to Prism and discover the ideal solution tailored to your needs.

Prism is also listed in these categories:

Last Updated: October 07, 2025

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All Competitors and Alternatives to Prism

HORIZON LIMS is a comprehensive laboratory information management system designed to streamline laboratory workflows and enhance efficiency. With its user-friendly interface, HORIZON LIMS allows laboratories to manage samples, track testing processes, and ensure compliance with regulatory standards seamlessly. The software facilitates real-time data access and reporting, enabling laboratory person... Read more about HORIZON LIMS

Free Trial

NA

Pricing Type

Contact Vendor

Location

United States

Labgen LIS is a powerful laboratory information system (LIS) software designed to streamline the operations of medical laboratories. The platform offers tools for managing laboratory workflows, tracking samples, and generating accurate test results. Labgen LIS allows laboratories to automate key processes, from sample collection to result reporting, reducing manual errors and improving overall eff... Read more about Labgen LIS

Free Trial

NA

Pricing Type

$5000 Per one-time

Location

United States

LigoLab LIS & RCM Operating Platform is a comprehensive medical lab software solution that combines laboratory information management with revenue cycle management (RCM) to optimize lab operations and financial performance. This platform offers a suite of tools for managing lab workflows, from sample tracking and test result processing to billing and claims management. With LigoLab, users can stre... Read more about LigoLab LIS & RCM Operating Platform

Free Trial

NA

Pricing Type

Contact Vendor

Location

United States

OmniStar Research is a comprehensive Clinical Trial Management Software (CTMS) designed to support the planning, execution, and management of clinical trials. This software simplifies the often complex processes of managing trial logistics, participant data, study timelines, and regulatory requirements. OmniStar Research provides researchers with tools for tracking patient recruitment, data collec... Read more about OmniStar Research

Free Trial

NA

Pricing Type

Contact Vendor

Location

Australia

Prolis is an advanced medical billing software designed to streamline billing processes for healthcare providers. This powerful tool offers features such as claims management, invoicing, and revenue cycle management, ensuring timely and accurate billing. With its user-friendly interface, users can easily track claims status, generate reports, and manage payments efficiently. Prolis supports integr... Read more about Prolis

Free Trial

Available

Pricing Type

Contact Vendor

Location

United States

quattro/CM is an advanced medical lab software designed to enhance the efficiency and accuracy of laboratory operations. The platform offers comprehensive tools for sample management, data tracking, and reporting. With its intuitive interface, users can easily manage laboratory workflows, track sample statuses, and ensure compliance with regulatory standards. quattro/CM supports integration with v... Read more about quattro/CM

Free Trial

Available

Pricing Type

$1500 Per one-time

Location

Germany

SciNote is a comprehensive medical lab software designed to streamline laboratory operations and ensure compliance with regulatory standards. The platform provides tools for managing experiments, tracking samples, and documenting lab results in a secure, paperless environment. SciNote supports collaboration among lab teams by offering shared access to data, experiment protocols, and project update... Read more about SciNote

Free Trial

Available

Pricing Type

$0.01 Per user

Location

United States

sLis is a versatile medical lab software designed to optimize laboratory operations and improve data management. The software provides features such as sample tracking, test result reporting, and compliance management, ensuring that labs can efficiently handle a high volume of samples while maintaining quality standards. sLis also integrates with laboratory instruments and existing health informat... Read more about sLis

Free Trial

NA

Pricing Type

Contact Vendor

Location

Greece

The enterprise work management platform

Smartsheet is a versatile work management and automation tool that simplifies complex tasks. With a spreadsheet-like interface, users can easily create, organize, and collaborate on sheets. These sheets serve as dynamic project plans, allowing for real-time updates and seamless collaboration. Smartsheet's grid structure makes it easy to track tasks, deadlines, and dependencies. Automation features... Read more about Smartsheet

Free Trial

30 Days

Pricing Type

$9 Per month

Location

United States

Document Control is a robust software solution designed to manage, organize, and secure important documents within organizations. It offers a centralized repository where users can store, categorize, and retrieve documents with ease, eliminating the inefficiencies of traditional paper-based systems. Document Control’s intuitive interface allows for seamless document uploading, version control, a... Read more about Document Control

Free Trial

Available

Pricing Type

$752 Per year

Location

United States

TELCOR RCM is an advanced medical billing software designed to streamline revenue cycle management for healthcare providers. This platform provides comprehensive tools for managing billing processes, tracking claims, and ensuring compliance with healthcare regulations. Users can easily generate invoices, monitor payment status, and analyze financial performance through customizable reporting. With... Read more about TELCOR RCM

Free Trial

NA

Pricing Type

Contact Vendor

Location

United States

Clinicea is an innovative electronic medical records (EMR) software designed to enhance patient care and streamline administrative processes in healthcare settings. This platform offers a comprehensive suite of tools that enable healthcare providers to manage patient records, appointments, billing, and reporting efficiently. With its user-friendly interface, Clinicea allows medical professionals t... Read more about Clinicea

Free Trial

Available

Pricing Type

$59 Per user

Location

Singapore

CloudLIMS is a powerful laboratory information management system (LIMS) designed to enhance efficiency and accuracy in laboratory operations. This cloud-based solution allows labs to manage data, track samples, and automate workflows seamlessly. With features like electronic lab notebooks, compliance tracking, and audit trails, CloudLIMS ensures that laboratories meet regulatory standards while op... Read more about CloudLIMS

Free Trial

NA

Pricing Type

$162 Per user

Location

United States

Dendi LIS is a powerful Laboratory Information System designed to streamline laboratory operations and enhance data management. Tailored for clinical laboratories, it facilitates efficient sample tracking, test result management, and data reporting. With a user-friendly interface, Dendi LIS allows lab technicians and administrators to manage workflows seamlessly, ensuring accuracy and compliance w... Read more about Dendi LIS

Free Trial

NA

Pricing Type

$1250 Per feautre

Location

United States

FAQs About Prism Alternatives

Some of the best alternatives to Prism include Smartsheet, OnCore, SciNote, Document Control, LigoLab LIS & RCM Operating Platform, CloudLIMS, Clinicea, TELCOR RCM, HORIZON LIMS, quattro/CM, Dendi LIS, Labgen LIS, Prolis, sLis and OmniStar Research. These alternatives offer similar features, better pricing, and more flexibility depending on your business needs.

There are various reasons why users look for alternatives to Prism, such as pricing concerns, missing features, better integration options, or improved customer support. Exploring alternative solutions ensures that businesses find the best fit for their specific requirements.

Yes! Depending on the product, you may find:

  • Free Trial options like Smartsheet, SciNote, Document Control, Clinicea, quattro/CM and Prolis (test premium features before subscribing).

These no-cost or low-cost alternatives can be ideal for startups and small businesses with budget constraints, but often come with feature limitations or usage caps. Always check each option’s details to ensure it fits your specific needs.

Small businesses looking for an easy-to-use and cost-effective alternative to Prism can consider Smartsheet, OnCore, SciNote, Document Control, LigoLab LIS & RCM Operating Platform, CloudLIMS, Clinicea, TELCOR RCM, HORIZON LIMS, quattro/CM, Dendi LIS, Labgen LIS, Prolis, sLis and OmniStar Research. These software options offer affordable pricing, simple setup, and essential business features tailored for growing teams.

Enterprises seeking a robust alternative to Prism can explore Smartsheet. These platforms offer scalability, advanced automation, top-tier security, and enterprise-grade customer support to meet large-scale business needs.

Some of the best cloud-based alternatives to Prism include Smartsheet, OnCore, SciNote, Document Control, LigoLab LIS & RCM Operating Platform, CloudLIMS, Clinicea, TELCOR RCM, HORIZON LIMS, quattro/CM, Dendi LIS, Labgen LIS, Prolis and OmniStar Research. These platforms offer seamless remote access, real-time collaboration, automatic updates, and enhanced security for smooth software management.

Yes, most Prism alternatives provide mobile apps for iOS and Android. Options like Smartsheet, Clinicea and Labgen LIS offer full-featured mobile applications that allow users to manage tasks, track progress, and collaborate on the go.

In conclusion, while Prism offers a robust solution for laboratory management, organizations should carefully evaluate alternatives like Smartsheet, sLis, HORIZON LIMS, and others. Each platform, including Prolis, Labgen LIS, and LigoLab LIS, presents unique features tailored to specific needs, such as RCM capabilities and document control. Solutions like TELCOR RCM and CloudLIMS excel in revenue cycle management and cloud-based operations, respectively. Ultimately, the choice depends on individual laboratory requirements, budget constraints, and desired functionalities, ensuring that the selected system aligns with operational goals and enhances overall efficiency.