Best Online Endpoint Protection Software

In an always-connected world, many businesses prefer endpoint protection software solutions that require no local installation. Below, you’ll find top online endpoint protection software platforms—often referred to as cloud-based or web-based—offering easy subscription models, automatic updates, and seamless remote access. Explore these recommended tools to streamline workflows, enhance collaboration, and keep your team productive from anywhere.

Last Updated: October 01, 2025

  • All Software All Software

254 Software

Popular Picks in Endpoint Protection Software

Sponsor

NinjaOne

NinjaOne

Contact Vendor

ESET Endpoint Security

ESET Endpoint Security

$211 Per year

Bitdefender GravityZone

Bitdefender GravityZone

$77.69 Per year

GlobalProtect

GlobalProtect

Contact Vendor

List of Top Web-Based Endpoint Protection Software

Pricing Options

Monthly Subscription

Annual Subscription

One-Time Payment

Quote Based

Features

No Features

Company Size

Self Employed

Small Business

Medium Business

Enterprise

I'm looking for Endpoint Protection Software that is:

Top-rated UEM & IT Management Software

NinjaOne is an effective patch management software designed to simplify and automate the process of keeping systems updated and secure. With its user-friendly interface, IT administrators can easily manage patches for various operating systems and applications across their networks. The software automates the identification of missing patches and allows for scheduled deployments, ensuring that dev... Read more about NinjaOne

Free Trial

Available

Pricing Type

Contact Vendor

Location

United States

ESET Endpoint Security is a robust solution for businesses seeking to fortify their cyber defenses. It stands out with its multi-layered security approach, combining traditional antivirus with advanced techniques like machine learning. This mix ensures effective defense against viruses, malware, and emerging threats. Unique to ESET is its low system footprint, ensuring security without compromisin... Read more about ESET Endpoint Security

Free Trial

Available

Pricing Type

$211 Per year

Location

Slovakia

Next-gen business AV to detect, prevent, and mitigate cyber threats effectively.

Bitdefender GravityZone is an advanced cybersecurity software suite developed to provide comprehensive protection for businesses of all sizes. Its key strength lies in its multi-layered defense mechanism, which includes antivirus, anti-malware, firewall, and ransomware protection. Notably, GravityZone employs machine learning and behavioral analysis to proactively detect and block new and evolving... Read more about Bitdefender GravityZone

Free Trial

NA

Pricing Type

$77.69 Per year

Location

Romania

Disrupt ransomware with industry-leading endpoint security on any platform.

Microsoft Defender for Endpoint is a comprehensive security solution tailored for enterprise environments. Its standout feature is 'Threat and Vulnerability Management', which proactively identifies and resolves security weaknesses. The software excels in 'Automated Investigation and Remediation', significantly reducing the workload on IT teams by addressing threats automatically. 'Endpoint Detect... Read more about Microsoft Defender for Endpoint

Free Trial

NA

Pricing Type

Contact Vendor

Location

United States

Microsoft Defender for Office 365 is an advanced email security software that protects businesses from phishing attacks, malware, and other email-based threats. It provides real-time protection against malicious attachments, links, and impersonation attempts, reducing the risk of data breaches and compromised accounts. The platform integrates seamlessly with Microsoft Office 365, offering automate... Read more about Microsoft Defender for Office 365

Free Trial

NA

Pricing Type

Contact Vendor

Location

United States

Microsoft Enterprise Mobility + Security (EMS) is a comprehensive suite of mobile device management (MDM) and security solutions designed to help businesses protect their data and manage devices in an increasingly mobile-first world. EMS combines identity and access management, device management, and advanced security features to secure corporate data across a variety of devices and platforms. Fea... Read more about Microsoft Enterprise Mobility + Security

Free Trial

NA

Pricing Type

$20 Per user

Location

United States

Microsoft Defender for Business is an advanced endpoint detection and response (EDR) software designed to protect small and medium-sized businesses (SMBs) from cyber threats. The platform provides comprehensive protection across devices, networks, and identities, with features such as real-time malware detection, ransomware protection, and threat intelligence. Microsoft Defender uses machine learn... Read more about Microsoft Defender for Business

Free Trial

Available

Pricing Type

$3 Per user

Location

United States

Continue your journey and help your team stay connected, protected, and efficient while on the go.

IBM Security MaaS360 is a comprehensive cloud-based mobile management solution developed for the modern workplace. It excels in ensuring security and management for devices, applications, and content across various platforms, including iOS, Android, and Windows. MaaS360 simplifies mobile device management (MDM) by offering intuitive controls for overseeing employee devices remotely. Notably, it fe... Read more about IBM Security MaaS360

Free Trial

NA

Pricing Type

$3 Per user

Location

United States

CylanceENDPOINT revolutionizes endpoint protection by using AI-driven technology to prevent malware and cyber threats before they can cause damage. Unlike traditional security solutions, CylanceENDPOINT uses machine learning to predict and neutralize potential threats with minimal impact on system resources. Its proactive approach eliminates the need for frequent updates, ensuring continuous prote... Read more about CylanceENDPOINT

Free Trial

NA

Pricing Type

Contact Vendor

Location

United States

Cisco AnyConnect Secure Mobility Client v4.x

Cisco AnyConnect is a reliable VPN software designed to provide secure remote access to corporate networks and resources. This platform enables organizations to protect sensitive data by encrypting internet traffic, ensuring that employees can work safely from anywhere. With Cisco AnyConnect, users can connect to their corporate network seamlessly, allowing for access to applications, files, and r... Read more about Cisco AnyConnect

Free Trial

NA

Pricing Type

Contact Vendor

Location

United States

Secure Cloud Analytics is now part of Cisco XDR.

Cisco Secure Cloud Analytics is an advanced cybersecurity software designed to provide organizations with comprehensive visibility and protection against emerging threats in cloud environments. This powerful platform leverages machine learning and behavioral analysis to monitor network activity, detect anomalies, and respond to potential security incidents in real time. Cisco Secure Cloud Analytic... Read more about Cisco Secure Cloud Analytics

Free Trial

Available

Pricing Type

$600 Per feautre

Location

United States

Cisco Secure Endpoint is an advanced network security software solution designed to provide comprehensive protection against threats across various endpoints. With its powerful detection and response capabilities, the software helps organizations identify and mitigate risks in real time. Cisco Secure Endpoint uses machine learning and behavioral analysis to recognize suspicious activities, enablin... Read more about Cisco Secure Endpoint

Free Trial

Available

Pricing Type

Contact Vendor

Location

United States

Box KeySafe is an encryption software solution designed to provide businesses with secure data protection and control over their encryption keys. With Box KeySafe, organizations can ensure that sensitive data, such as financial records, intellectual property, and personal customer information, is encrypted both in transit and at rest. The software allows businesses to manage their own encryption k... Read more about Box KeySafe

Free Trial

NA

Pricing Type

Contact Vendor

Location

United States

Simple, GUI-based firewall appliance management

Cisco Adaptive Security Device Manager (ASDM) is an endpoint protection software that helps businesses manage and monitor their network security devices. ASDM provides an intuitive graphical interface for configuring and monitoring Cisco ASA firewalls, VPNs, and security policies. The platform includes tools for real-time threat analysis, policy management, and device status monitoring, allowing n... Read more about Cisco Adaptive Security Device Manager (ASDM)

Free Trial

NA

Pricing Type

Contact Vendor

Location

United States

Clear verdict. Decisive action. AI speed.

Cisco XDR (Extended Detection and Response) is a comprehensive cybersecurity solution designed to provide advanced threat detection, investigation, and response capabilities across your entire organization. Built to integrate with a wide range of IT and security infrastructure, Cisco XDR leverages artificial intelligence and machine learning to analyze and correlate data from endpoints, networks, ... Read more about Cisco XDR

Free Trial

NA

Pricing Type

Contact Vendor

Location

United States

Carbon Black Endpoint is a cuttingedge cybersecurity software designed to protect organizations from advanced threats and cyberattacks. With its proactive threat detection capabilities, Carbon Black continuously monitors endpoint activities to identify and respond to suspicious behaviors in realtime. The platform employs advanced machine learning algorithms to analyze data and provide actionable i... Read more about Carbon Black Endpoint

Free Trial

NA

Pricing Type

Contact Vendor

Location

United States

Workspace ONE is a mobile device management (MDM) and enterprise mobility management (EMM) software designed to help businesses secure and manage the devices and applications used by their workforce. The platform provides a unified endpoint management solution that supports various devices, including smartphones, tablets, and laptops, regardless of the operating system. Workspace ONE allows IT adm... Read more about Workspace ONE

Free Trial

Available

Pricing Type

Contact Vendor

Location

United States

VMware AppDefense is a sophisticated endpoint protection software designed to help organizations safeguard their applications and data from advanced threats. The platform provides tools for monitoring application behavior, detecting anomalies, and responding to security incidents in real-time. VMware AppDefense allows users to establish a security posture based on the expected behavior of applicat... Read more about VMware AppDefense

Free Trial

NA

Pricing Type

Contact Vendor

Location

United States

cb Defense is a robust endpoint protection software designed to safeguard organizations from cyber threats and ensure the security of their digital assets. This platform provides comprehensive protection against malware, ransomware, and other advanced threats by leveraging advanced machine learning and behavioral analysis techniques. cb Defense features an intuitive dashboard that allows IT admini... Read more about cb Defense

Free Trial

NA

Pricing Type

Contact Vendor

Location

Japan

VMware Cloud Director Availability is a business continuity software designed to help businesses ensure high availability and disaster recovery for their cloud infrastructure. The platform provides tools for replicating workloads, migrating virtual machines, and ensuring continuous access to critical applications and data. VMware Cloud Director Availability includes features such as automated fail... Read more about VMware Cloud Director Availability

Free Trial

Available

Pricing Type

Contact Vendor

Location

United States

All-in-one protection for devices, data, and people.

Avast Endpoint Protection is a tailored security solution for businesses, emphasizing network and device safety. One of the key features includes 'Smart Scan,' which swiftly identifies vulnerabilities and malware, ensuring minimal disruption to business operations. The software's 'Firewall Management' provides robust network protection, controlling what enters and leaves the system. A standout is ... Read more about Avast Endpoint Protection

Free Trial

NA

Pricing Type

Contact Vendor

Location

Czech Republic

Best-in-class endpoint protection against ransomware & zero-day threats, backed by powerful data security.

ESET PROTECT Advanced stands out as a comprehensive security solution, particularly for businesses. Its 'Multi-Layered Protection' feature effectively guards against ransomware and zero-day attacks, ensuring robust defense. A key aspect is the 'Cloud Sandbox' technology, which analyzes suspicious files in an isolated environment, enhancing threat detection. The software includes 'Full Disk Encrypt... Read more about ESET PROTECT Advanced

Free Trial

NA

Pricing Type

Contact Vendor

Location

Slovakia

Symantec Enterprise Cloud is a powerful compliance software solution designed to help organizations manage their regulatory obligations and protect sensitive data. This platform offers a comprehensive suite of tools for risk assessment, policy management, and compliance reporting. Users can easily monitor their compliance status in real-time, identify potential risks, and ensure adherence to indus... Read more about Symantec Enterprise Cloud

Free Trial

NA

Pricing Type

Contact Vendor

Location

United States

Symantec Endpoint Detection and Response (EDR) is an industry-leading software solution designed to protect organizations from sophisticated cyber threats. Leveraging advanced analytics and machine learning, Symantec EDR provides comprehensive visibility into endpoint activities, enabling security teams to detect, investigate, and respond to potential threats in real time. The platform’s intuiti... Read more about Symantec Endpoint Detection and Response

Free Trial

Available

Pricing Type

Contact Vendor

Location

United States

Avast Premium Business Security is an advanced endpoint protection software designed to safeguard businesses against a wide range of cyber threats. This platform offers comprehensive security features, including real-time antivirus protection, firewall management, and ransomware shielding, ensuring that sensitive data remains secure. Avast’s intuitive dashboard provides IT teams with visibility ... Read more about Avast Premium Business Security

Free Trial

Available

Pricing Type

$46.99 Per user

Location

NA

Explore Today’s Featured List of Top Web-Based Endpoint Protection Software

SysCloud is a versatile cloud management software designed to optimize and secure cloud environments for businesses of all sizes. It offers a comprehensive suite of tools for provisioning, monitoring, and managing cloud resources, ensuring efficient utilization and cost-effectiveness. SysCloud features automated scaling, resource allocation, and performance analytics, enabling organizations to mai... Read more about SysCloud

Free Trial

Available

Pricing Type

$38 Per user

Location

United States

Securden

The Easiest Privileged Access Management (PAM) Platform

Securden is a cutting-edge cybersecurity software solution designed to protect organizations from evolving threats and vulnerabilities. This platform offers a suite of tools for privileged access management, password management, and compliance management, ensuring that sensitive data remains secure. Securden’s intuitive interface allows users to manage and monitor access permissions effectively,... Read more about Securden

Free Trial

Available

Pricing Type

Contact Vendor

Location

United States

Sternum EIV is an advanced endpoint protection software specifically designed to secure embedded systems and IoT devices from a range of cybersecurity threats. This platform provides comprehensive security features, including real-time monitoring, threat detection, and automated response capabilities, tailored to address the unique challenges faced by connected devices. Sternum EIV continuously as... Read more about Sternum EIV

Free Trial

Available

Pricing Type

$1 Per feautre

Location

Israel

No buyer guide found.