Best AI-Powered Endpoint Protection Software

AI Endpoint Protection Software provides advanced defense against cyber threats by protecting all connected devices within a network. Unlike traditional solutions, AI-powered endpoint protection tools learn from user behavior, identify unusual activities, and block potential attacks instantly. They combine antivirus, anti-malware, intrusion detection, and real-time threat intelligence to secure business operations. These solutions are especially critical for companies with remote employees or cloud-based infrastructures, where endpoints often become the weakest link. By using AI endpoint security software, businesses can prevent ransomware, data breaches, and insider threats while ensuring compliance with security standards. With automated updates, centralized management, and strong analytics, these solutions make cybersecurity easier and more effective for enterprises of all sizes. Find the ideal AI Endpoint Protection Software to safeguard every device across your network.

Last Updated: October 01, 2025

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17 Software

Popular Picks in Endpoint Protection Software

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NinjaOne

NinjaOne

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ESET Endpoint Security

ESET Endpoint Security

$211 Per year

Bitdefender GravityZone

Bitdefender GravityZone

$77.69 Per year

GlobalProtect

GlobalProtect

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List of Top AI Endpoint Protection Software Solutions

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World-Leading Cybersecurity. Powered by AI.

SentinelOne is a leading Endpoint Protection Software designed to safeguard businesses against a wide range of cyber threats, including malware, ransomware, and advanced persistent threats (APTs). This robust platform leverages artificial intelligence and machine learning to provide real-time protection, detection, and response across all endpoints within an organization. SentinelOne features auto... Read more about SentinelOne

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Available

Pricing Type

$179.99 Per feautre

Location

United States

The Anomali Platform is a leading risk management software designed to help organizations proactively identify and mitigate cybersecurity threats. This comprehensive platform provides advanced threat intelligence capabilities, enabling users to analyze and correlate data from various sources. The Anomali Platform features an intuitive dashboard that presents critical threat metrics and alerts, all... Read more about The Anomali Platform

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Location

United States

Deep Instinct is a leading endpoint protection software that uses deep learning to prevent cyber threats before they impact devices. It offers a proactive approach to endpoint security, detecting and stopping malware, ransomware, and other attacks in real-time. Deep Instinct continuously analyzes network activity, providing unmatched accuracy in threat detection. The software's AI-driven technolog... Read more about Deep Instinct

Free Trial

Available

Pricing Type

$40 Per year

Location

United States

Industry-Leading Cloud Security Solution

Orca Security is a game-changing cybersecurity platform that redefines cloud security for organizations. This innovative software uniquely uses SideScanning™ technology to seamlessly and comprehensively assess your cloud environment, without the need for intrusive agents or network scanners. Orca Security's standout feature lies in its ability to instantly identify vulnerabilities, misconfigurat... Read more about Orca Security

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Location

United States

Be the guardian of the cyberspace. Hyperautomate your operations.

TEHTRIS XDR Platform is an extended detection and response (XDR) software that provides comprehensive cybersecurity protection across an organization’s IT environment. This platform integrates threat detection, response, and remediation capabilities, enabling security teams to detect and neutralize cyber threats in real-time. TEHTRIS XDR consolidates data from multiple security tools, providing ... Read more about TEHTRIS XDR Platform

Free Trial

NA

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Location

France

We Know the IPs Attacking You — Do You?

Crowdsec is a collaborative cybersecurity software designed to protect organizations from a wide range of online threats by leveraging community-driven intelligence. This platform provides tools for monitoring and responding to security incidents in real time, allowing users to detect and mitigate attacks effectively. Crowdsec’s unique approach involves gathering data from its global community o... Read more about Crowdsec

Free Trial

Available

Pricing Type

$29 Per month

Location

France

World First Visual AI Based Malware Detection

INLYSE Malware.AI is an advanced antivirus software powered by artificial intelligence (AI) to protect devices from malware, viruses, and other cyber threats. The software uses machine learning algorithms to detect and block threats in real-time, offering proactive protection against known and unknown malware. INLYSE Malware.AI continuously monitors network activity, analyzing files, emails, and w... Read more about INLYSE Malware.AI

Free Trial

Available

Pricing Type

$2.5 Per user

Location

Germany

Broadcom is a DevOps software that provides comprehensive tools for automating software development, testing, and deployment processes, enabling faster, more efficient delivery of applications. The platform supports continuous integration and continuous deployment (CI/CD), allowing development teams to automate builds, run tests, and deploy changes seamlessly. Broadcom’s monitoring and logging f... Read more about Broadcom

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Location

United States

Essential device and identity protection

McAfee AntiVirus Plus is a robust security software designed to protect your devices from various cyber threats. Its standout feature is the 'Real-Time Scanning,' which continuously monitors your system, instantly detecting and removing viruses and malware. The software supports multiple devices, ensuring your PCs, Macs, and smartphones are secure. With 'QuickClean,' it improves your device's perf... Read more about McAfee AntiVirus Plus

Free Trial

NA

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Location

United States

The best antivirus App to protect your iOS and Android devices.

Trend Micro Mobile Security is a comprehensive security application developed to protect smartphones and tablets from a wide range of digital threats. It stands out for its robust anti-malware technology, which actively scans for and blocks viruses, spyware, and other malicious software. The software includes a web protection feature that safeguards against phishing and malicious websites, enhanci... Read more about Trend Micro Mobile Security

Free Trial

NA

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Location

Japan

Stop attacks with AI-powered endpoint security

Cortex XDR is an advanced endpoint protection software developed by Palo Alto Networks that integrates multiple layers of security to protect organizations from a wide range of cyber threats. Combining network, endpoint, and cloud security into a single platform, Cortex XDR provides comprehensive protection against malware, ransomware, phishing attacks, and other types of cyber threats. The softwa... Read more about Cortex XDR

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Location

United States

Trellix Network Detection & Response is a powerful cybersecurity software solution that provides advanced network protection against evolving cyber threats. With its real-time threat detection capabilities, Trellix Network Detection & Response identifies suspicious activities across network traffic and responds proactively to potential security breaches. The software leverages machine learning and... Read more about Trellix Network Detection & Response

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NA

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Location

United States

Trellix Endpoint Security is a comprehensive computer security software designed to protect organizational devices from a wide array of cyber threats. This robust platform offers features such as antivirus and anti-malware protection, firewall management, intrusion prevention, and endpoint detection and response (EDR), ensuring comprehensive defense for desktops, laptops, and mobile devices. Trell... Read more about Trellix Endpoint Security

Free Trial

NA

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Location

United States

Secure the Human Layer. Contain the Mobile Threat.

Lookout is an advanced cybersecurity software solution designed to protect mobile devices and sensitive data from evolving cyber threats. This platform offers comprehensive security features, including malware detection, data encryption, and secure browsing, ensuring users can operate safely in today’s digital landscape. Lookout’s user-friendly interface makes it easy for individuals and organ... Read more about Lookout

Free Trial

Available

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Location

United States

Ivanti Connect Secure is a robust privileged access management (PAM) software designed to secure and manage access to critical systems and sensitive data within organizations. It offers a comprehensive platform for controlling, monitoring, and auditing privileged user access, ensuring that only authorized personnel can access high-risk systems. Ivanti Connect Secure’s intuitive interface allows ... Read more about Ivanti Connect Secure

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Available

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Location

United States

Heimdal Ransomware Encryption Protection is an endpoint protection software designed to guard against ransomware attacks and encrypted data threats. The platform offers proactive protection by detecting and blocking ransomware before it can encrypt files. Heimdal Ransomware Encryption Protection includes real-time monitoring, threat intelligence, and behavioral analysis to identify suspicious acti... Read more about Heimdal Ransomware Encryption Protection

Free Trial

Available

Pricing Type

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Location

Denmark

Heimdal XDR is a powerful Managed Service Provider (MSP) software designed to enhance cybersecurity management for service providers. This platform provides comprehensive tools for threat detection, incident response, and network monitoring, ensuring that MSPs can deliver robust security solutions to their clients. With features such as real-time threat intelligence, automated incident response, a... Read more about Heimdal XDR

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Available

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Location

Denmark

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Frequently Asked Questions

It’s a tool that safeguards endpoints like laptops and mobiles using AI-driven threat detection.

It monitors device activity, identifies anomalies, and blocks malicious behavior in real time.

Yes, because it uses behavioral analysis instead of just virus signatures.

Yes, most AI endpoint tools support remote and hybrid work environments.

Malware, ransomware, phishing, and data breaches.

No, modern tools are user-friendly with automated protection.

Banking, healthcare, education, and IT companies.

Yes, most solutions provide full cloud compatibility.

Pricing depends on endpoints covered and features offered.

Continuous monitoring and proactive threat prevention.